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OCR: trophic The role of corticotrophin (adrenocortic n is not epleted hormone: ACTH) in aldosterone secreti entirely clear; it is more effective in salt- alance, and subjects than in those with normal salt b normal is probably relatively unimportant in the xistence of situation. There is also evidence of the e other factors, as yet unknown. stimulates Although acute administration of ACTI ess is aldosterone secretion, chronic ACTH ex ls of associated with normal or even low leve tensin aldosterone. Thus, when the renin-angi ents with play an system is suppressed, for example in pat primary hyperaldosteronism, ACTH ma important role.